Category Archives: In the Spotlight

Big pharma, at home and outsourced

When I was in college, a friend told me something that sounded too good to be true: I could get paid forty dollars for a blood test. And if I didn’t have a history of a certain symptom, they would pay me forty dollars every month for the next two years in exchange for more blood tests. They were in the last year of signing up subjects for a clinical trial (something I’d read about in my biochemistry classes) on a common, as-of-yet uncured disease for which a bigger pharmaceutical company had developed a vaccine. There were no abnormal reactions worse than those of a flu shot, and I might get the placebo, making the whole thing even more of a walk in the park. The first nurse I talked to assured me that during the trial, anyone contracting the disease would receive immediate and free treatment for as long as it was required, even if they had been on the placebo.

If the above sounds like your dream job, you can be a guinea pig, joining the ranks of many familiar faces from Western popular culture. Medical test subject was the entry-level occupation in the first version of The Sims, and is featured a few times on the Simpsons. When Bart gets expelled, he imagines a future testing dangerous food additives; the “2-4-dexoxypropaniramine” in Nature’s Goodness, a new diet soft drink, mutates him into a hulking beast (whereupon the lead scientist remarks “pleasing taste, slight monsterism”). In a different episode, Homer signs up to be a guinea pig at the “Screaming Monkey Research Lab” where he goes blind from a diet pill.

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Posted in Quick Thoughts | 4 Comments

Reuniting STS with HPS

Boaz Miller

I have recently attended a talk by Harvard Professor Sheila Jasanoff at Bar Ilan University’s STS Program. Jasanoff is one of the founding members of the field of STS (which stands for “Science and Technology Studies” or “Science Technology & Society ” aka “Science Studies” and “Social Studies of Science” – which tells you something about its fragmented history). She talked about the history of STS and her vision of its future.

Jasanoff’s talk was partly a response to a recent attack on STS by historian of science Professor Lorraine Daston1 on behalf of the older sister discipline of history of science. Daston has argued that while both STS and history of science drew the lesson that science is social from Thomas Kuhn’s influential book The Structure of Scientific Revolutions (1962), they have interpreted it differently. Historians of science (cultural historians, to be precise, who for Daston are the most dominant today) have interpreted “social” as “historically situated in a particular culture”. They drew the right lesson which is that science should be studied in its historical context without historians’ imposing their present knowledge back on the past. By contrast, STS scholars interpreted “social” as “political”, and drew the wrong lesson that science should be studied like politics. Consequently, STS scholars have been applying general political or quasi-political theoretical frameworks to different case studies from science. These frameworks presuppose that science is basically the same in different periods, and hence can be analyzed in the same terms. By doing that, STS scholars have abandoned the study of what science is, or so Daston argues.

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  1. Daston, Lorraine. 2009. Science Studies and the History of Science. Critical Inquiry 35(4): 798-813.
Posted in In the Spotlight | 10 Comments

Countdown to Re-entry

Jonathan Turner

David Pugliese of Postmedia News broke the story on Monday January 3rd that the Canadian Space Agency (CSA) and Defence Research and Development Canada (DRDC) want to make the development of a Canadian rocket a high priority.1  The justification follows the normal rationales: Canada currently relies on other countries (bad for sovereignty), native capabilities exist and should be fostered (good for Canadian labs and industries), and a niche market might develop that Canada could fill (excellent for the economy). In other words, there are several proponents of rocketry and they are trying to drum up popular support through the Conservative-friendly media outlet. The plan will probably collapse before any rockets are ever launched, but in the immediate future we can at least expect the usual suspects to study the idea and issue several position papers in favour of the plan.

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Science and the Media: Upside-Down Pyramid Thinking

Greg Lusk

This is the second post to appear in our new section called “quick thoughts.” The aim of this section is to raise an issue for comment in more detail than the weekly roundup does, but in a more succinct format than our longer 1000 word posts. We hope that this section will turn the spotlight onto those that choose to comment, rather than the author of the post.

I’ve been reading Naomi Oreskes’ book Merchants of Doubt, which I will review for Spontaneous Generations and post here on the Bubble Chamber as well. I will save my comments for that review, but the book, and a recent lunch conversation with philosophers and HPSers, has me thinking a lot about how the media reports on events within the scientific community.

While I was a master’s student, I was course instructor for “Phil120 – Introduction to Logic,” which was interestingly enough a required course for the school of journalism (I have a hot chili on ratemyprofessor.com, in case you were wondering). The second and third year journalism students, who constituted a majority of my class, did not understand why they needed to take the course, and they were vocal about it. As a response to this, and to low marks across the board, I gave an extra credit assignment: Use your journalism skills and interview a professor or administrator responsible for the inclusion of this class in your course requirements. Respond to this interview with your own arguments, either for or against the position presented.

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The Murky Climate of the “Editorial Peer Review” Debate

Peer review was a popular topic in 2010. Not that it hadn’t been discussed in the media before, but it seems the issue popped up more than ever over the past year. Here, I’ll use three examples among many1 from 2010, which have led to calls for strengthening, “tweaking”, or abolishing the editorial peer review system. The dominant discourses reveal a disconnect both at the level at which peer review is being analyzed and regarding the expectations of the process. Editorial peer review is not a “gold standard”, nor a way of producing scientific knowledge; it is difficult to categorically say whether it “works” or not. It is equally problematic to systematically dismiss editorial peer review as only a basic means of quality control that leaves all judgment to an ad hoc post-peer review process (though this approach is certainly effective under certain circumstances). In order to address concerns about peer review within a specific context, the process itself should be viewed as a set of practices, mainly used to demarcate boundaries (of science as a whole and of individual specialties) and to favour consensus building.

Arsenic, climate and clinical trials…

Mono Lake in California, where it was reported that high arsenic levels proved conducive to the evolution of arsenic-using microbes

Following the backlash from the “hype” of NASA’s public relations efforts, there was a major debate over whether the article in question should have published in the first place (or whether it was “worthy” of publication in Science). For others, the problem with this episode, like that of cold fusion 20 years ago, lay in a hasty “passage” to the public sphere. This implicitly means that institutionalized editorial peer review is the solution, not the problem. Other perspectives focused on the self-correcting nature of science, in this case mostly occurring as post-editorial peer review discussions. The blogosphere buzz around this article has indeed been something akin to a sort of extremely “inclusive” form of expanded peer review and is certainly interesting in its own right, especially as one considers the strengths and weaknesses of the “blog” model of peer review. But this “backlash” effect could hardly be considered a model for ensuring scientific accuracy.

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  1. See also, for instance: Mark Henderson, British Medical Journal, 340, 2010, which focuses on the “anonymity” of peer review.
Posted in In the Spotlight | Tagged | 1 Comment

How to pursue science from the humanities?

Greg Lusk

You may notice that this article appears in a new section called “quick thoughts.” The aim of this section is to raise an issue for comment in more detail than the weekly roundup does, but in a more succinct format than our longer 1000 word posts. We hope that this section will turn the spotlight onto those that choose to comment, rather than the author of the post.

There has been a lot of talk around my department about curriculum changes, and it has me thinking about the ideal HPS curriculum. I surfed around the web a bit looking at various departmental websites. My program, as well as some others, seems to be oriented towards science undergrads who have decided to enter the humanities. The more recent entering classes in my program have not fit this description, as it seems more and more students are coming from the humanities instead of the sciences. Science, no matter what the field, takes an immense amount of time to learn. It seems that there are not as many accommodations made for the humanities student wanting to learn science as there are for the science student wanting to enter the humanities – there is just not a push to train humanities students in the sciences. Where is a humanities graduate student going to get the time to train him or herself in science? This seems to be a problem with the HPS curriculum.

From what I hear this problem is endemic in history and philosophy of science. We all want to know more science and math; yet, we also want to graduate without taking on more debt than is necessary. Maybe I am just blowing the whole thing out of proportion. However, I bet those of us who enter the field from the humanities rather than the sciences feel more constrained within the field.

I hear about this problem in different fields of study as well. At the Canadian Science Policy Conference that I recently attended, many speakers pointed out the need for government representatives to have a knowledge of how science works. At the Canadian Congress of the Humanities and Social Sciences, a researcher’s survey data demonstrated that the most requested resource by public school science teachers in one Canadian province was not money or lab equipment, but rather “knowledge of science.” I am sure this problem also appears for those looking to work at the intersection between science and business, policy, or communications. It feels as if those in HPS need to be full time science students in addition to being full time humanities students. In a way there are obvious answers to this problem for the humanities grad student: either learn the material as you complete your degree, or take time off for intensive study and return to your degree later. But both of these options are easier said than done, especially if one is trying to avoid student debt.

Have any of our readers successfully navigated this problem and have advice? Are there programs that could help a humanities student further embrace his/her love of science and math? Should one just let these topics pass him/her by and concentrate on problems of a non-technical nature? Or should HPS departments be more attune to this desire?

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Between history of science and science policy: Moving from the “war room” to the “shop floor”

Most would agree that the history of science and science policy are somehow linked: the various incarnations of history of science as a field of study aim to uncover “how science works”, be it through a “traditional” focus on a more or less linear intellectual progression, through the lens of its relationship with a broader social and political sphere, or by looking at its deeper social interactions between scientists. In this sense, I’m convinced that almost any historian of science—especially those operating in the context of having to “justify” the impact of their work—would recognize, on some level, important connections between the knowledge they produce and science policy. One could even argue that the raison d’être of modern science policy lies in the realization that science itself does not operate as an isolated endeavour—it’s too important to be run only by practicing scientists. But can we say something more specific about what ties the history of science and science policy in the making? I hope to put forth a few partial suggestions to help answer this question or, at the very least, provide some food for thought.

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Posted in In the Spotlight | 13 Comments

How to Philosophize About the Business and Bureaucracy of Science

Julia Bursten

In our post-Kuhnian times as philosophers and historians of science, it is important to remember that interests besides the holy, disinterested pursuit of Truth, Progress and Knowledge affect the development of scientific thought and practice. There is now a blossoming field of study devoted to understanding how scientific communities, personal and social values, and similar human concerns shape scientific developments. Recently, some people have taken another, quite pressing, (possibly?) nonscientific concern that affects the development of science: money.

This post is inspired by a group of people who are doing what might be called the Philosophy of the Business of Science: they are investigating the practicalities of funding and grant processing using philosophical tools for the purpose of trying to figure out how these aspects of the scientific endeavor shape changes in the landscape of science, and whether there are better systems that could, if implemented, improve this landscape. I had a chance to see a symposium on peer review in the sciences put on by a group of these people at the 2010 Philosophy of Science Association (PSA) biennial meeting in Montreal last weekend, and I want to share some of what I learned there with you. I also want to tell you a little bit about another pair of philosophers whose project is aimed more directly at funding structures in the sciences. But before I get into the gory details, let me orient you to the problems at hand.

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PSA Report: The Philosophy of Commercialized Science

Mike Thicke

This past weekend, November 4-7, Montreal was host to the annual meetings of the History of Science Society (HSS) and the Philosophy of Science Association (PSA). Many of us at The Bubble Chamber attended and presented our own work. Over the next couple of weeks we plan to offer reports and reflections on some of the sessions we attended. Starting things off, here is a report from a session on a topic that should be of particular interest to Bubble Chamber readers: “The Philosophy of Commercialized Science”. I’m not going to offer any commentary right now, but I think there’s still a lot of interesting information here!

Sergio Sismondo – Corporate Interests and Medical Science

Sergio Sismondo started off the session by telling us about the practice of ghost writing pharmaceutical studies. Most of us have probably heard that pharmaceutical companies often perform their own internal studies and pass off those studies to academics for “editing”, leading to the appearance that the study was independently conducted. Most of us have probably also heard that there is a huge bias in the published literature towards research findings favorable to pharmaceutical companies, and that that bias disappears when not counting studies sponsored by those companies. However, the details Sismondo presented were fascinating.

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Posted in In the Spotlight | 3 Comments

Reaching for the stars and staying down to earth

Curtis Forbes

Astronomers recently discovered an Earth-like planet, orbiting a Sun-like star, at an Earth-like distance, only 20 light years away. 1  The lead scientist in this project, Steven Vogt, has gone so far as to state that he is basically “100% certain” about the existence of life on the newly discovered world, a bet placed primarily on the planet’s distance from its sun.2  The only inhospitable-sounding part of most descriptions is the planet’s catalog-derived name – Gliese 581 g.

The subsequent public uptake of this discovery, for example by NBC’s Brian Williams, has gotten many people rightly concerned about the social consequences of generating hype about this astronomical discovery.  After reporting on this astronomical discovery during the nightly news, Williams finished his report by stating, “It’s just nice to know that if we screw this place up badly enough there is some place we can all go.”  David McConville, a science educator, responded with an avatar-based video, arguing that statements like Williams’s are routinely used to “subconsciously justify the continued destruction of our planetary ecosystems,” and that he should therefore retract his insinuation that Gliese 581 g could serve as a “back-up” Earth.  It’s not at all clear that he’s wrong about that.

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  1. This discovery has not gone undisputed, however.  Here is a discussion of the controversy surrounding this “finding”
  2. This claim has, rightly, come under intense criticism from astronomers.  As Mark Thompson put it, “We can’t even be 100% sure it’s made of rock!!!”
Posted in In the Spotlight | 6 Comments